What is the recommended dose of Succinylcholine?

The recommended dose of Succinylcholine for rapid sequence intubation and in emergency scenarios typically falls within the range of 1-2 mg/kg. This dosage is considered optimal for achieving effective neuromuscular blockade quickly, facilitating both intubation and procedures requiring muscle relaxation.

Succinylcholine is a depolarizing neuromuscular blocker that acts rapidly, and its administration at this dosage allows for quick onset of paralysis—usually within 30-60 seconds—making it particularly useful in urgent situations. The pharmacodynamics at this dosage balance effective muscle relaxation while minimizing the risk of potential adverse effects associated with higher doses, such as prolonged paralysis or hyperkalemia.

In clinical practice, it's essential to consider patient factors and the clinical context when administering any medication, including Succinylcholine, to ensure safety and efficacy. However, the established therapeutic range of 1-2 mg/kg is well-supported by guidelines and evidence within the emergency and critical care settings.