What does Combat Gauze activate in the clotting process?

Combat Gauze activates Factor XII in the clotting process. Factor XII, also known as Hageman factor, is a crucial component of the intrinsic pathway of coagulation. When Combat Gauze is deployed, it not only serves as a physical barrier to bleeding but also incorporates a cellulose-based material that interacts with Factor XII. This interaction triggers a cascade of events leading to the activation of the coagulation cascade, ultimately forming a stable blood clot.

The activation of Factor XII is particularly significant in traumatic situations where rapid hemostasis is critical. By enhancing the body's natural clotting response, Combat Gauze helps to control hemorrhage effectively in austere environments where immediate medical intervention might not be readily available.

In contrast, the other factors mentioned do not play as direct a role in the initial activities associated with the use of Combat Gauze for hemostasis. Factor X is involved later in the common pathway of coagulation, while Factors VII and II (Prothrombin) also play roles in coagulation but are not directly activated by the mechanism of Combat Gauze.