If there is a febrile reaction to a blood transfusion, what is a typical treatment?

In the context of a febrile reaction to a blood transfusion, the most appropriate management typically involves administering IV Acetaminophen to help reduce fever and provide symptomatic relief. This approach addresses the fever, which is often the most distressing symptom for the patient during such a reaction.

While stopping the transfusion is an important initial step upon recognizing a transfusion reaction, the question specifically asks about the treatment following that action. Additionally, intravenous fluids may be needed depending on the patient's overall condition but are not the primary treatment for febrile reactions. Antibiotics are typically reserved for suspected infections rather than straightforward febrile reactions after transfusions, which are usually not caused by infection. Therefore, the administration of IV Acetaminophen is the focus of treatment once the transfusion has been halted and is the most specific symptomatic intervention for a febrile transfusion reaction.